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Diclofenac+Serratiopeptidase is a combination medicine used to provide relief from pain. The medication belongs to a class of combination medications called NSAIDs (non-steroidal anti-inflammatory drugs) used to relieve pain and inflammation in conditions like osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. It can also be used to relieve muscle pain, tooth pain during dental surgery, menstrual period pain/cramps, ear pain, and migraine headaches. Diclofenac works by blocking the effect of a chemical messenger, known as cyclo-oxygenase (COX) enzymes that make other chemical prostaglandins, responsible for causing pain, swelling, and fever. Serratiopeptidase acts as a mucolytic and anti-inflammatory agent thereby decreasing swelling at the painful site. 

Take the medicine as per the prescribed dosage and duration and complete the course of the medicine. Do not crush, chew or break the tablet. Swallow the whole tablet with water. The most common side effects noticed on using Diclofenac+Serratiopeptidase tablets are nausea, vomiting, stomach pain, headache, indigestion, and diarrhea. Inform the doctor if you are allergic to Diclofenac or Serratiopeptidase, or similar medicines. Store the medicines in a cool and dry place away from direct sunlight. 

Uses of Diclofenac+Serratiopeptidase Tablets 

The medicine is composed of Diclofenac and Serratiopeptidase. Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) that works by blocking the release of certain chemical messengers in the brain that cause pain and inflammation (redness and swelling). Serratiopeptidase is an enzyme that works by breaking down abnormal proteins at the site of inflammation and promotes healing. The medication is used to provide relief from pain and inflammation associated with the following mentioned health conditions: 

  • osteoarthritis
  • muscle pain
  • joint pain
  • rheumatoid arthritis
  • mild migraine
  • dental pain

Side Effects of Diclofenac+Serratiopeptidase Tablets

There are mild to moderate side effects of Diclofenac+Serratiopeptidase Tablets that do not last for a long time. The side effects usually depend on the physiological condition and response to the medicine. If your side effects persist or get severe with time, immediately contact your doctor. The range of side effects noticed on using Diclofenac+Serratiopeptidase Tablets are mentioned following: 

  • Nausea
  • Vomiting
  • Diarrhea
  • Dizziness
  • Headache
  • Vertigo
  • Dyspepsia
  • Abdominal pain
  • Flatulence
  • Decreased appetite
  • Increased transaminase level in blood
  • Rash

Drug Interaction 

The drugs can interact with each other and cause several unpleasant health effects. Hence, it is advised to not take certain drugs in combination. Do not take Diclofenac+Serratiopeptidase Tablets in combination with the following mentioned drugs:

  • pain killers (aspirin, ibuprofen)
  • immunosuppressants (cyclosporine, tacrolimus)
  • anti-psychotic (lithium)
  • cardiac glycoside (digoxin)
  • blood thinner (warfarin)
  • anti-rheumatoid (methotrexate)
  • antacid (magnesium hydroxide)
  • anti-fungal (ketoconazole, miconazole, fluconazole, voriconazole)
  • anti-arrhythmic (amiodarone)
  • anti-gout (sulfinpyrazone)
  • anti-emetic (metoclopramide, domperidone)
  • bile acid sequestrant (cholestyramine)
  • anti-cancer (imatinib)
  • antibiotic (chloramphenicol)
  • anti-progestational steroid (mifepristone)
  • anti-diabetics
  • diuretics
  • anti-hypertensives medicines

Interaction with Disease: 

  • stomach ulcer or perforation
  • bleeding problems
  • bypass surgery
  • heart attack
  • blood circulation problems
  • inflammation of the intestines
  • anemia, heart
  • kidney or liver problems

Precautions and Warnings 

1. Avoid consuming alcohol as it may cause increased dizziness. It can also increase the risk of unpleasant health effects.

2. Consult your doctor before taking the Diclofenac+Serratiopeptidase Tablets as it may pose a potential risk for the baby and mother.

3. Keep the medicine out of reach of children and pets. Carefully dispose of expired and discarded medicines.

4. Store the medicines in a cool and dry place, away from direct sunlight.

5. Sticty follows the prescribed dosage and duration to avoid the risk of reinfection.

6. Consult your doctor immediately if you notice stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools.







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